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To remove from flesh you betadine (stains spines), tweezers, a needle, and some spare time. I normally handle mine with thin gloves or newspaper. When hiking in area with cactus and my dog, I always carried needle-nose pliers (he would collect them in his fur and pads).

soak it with espson salt and water/

Never thought of using betadine to stain Great idea and would make it sooooooo much easier to see. Thanks for the idea.